Publish Date:  Mar 24, 2026

Milano, IT Bologna, IT

Senior Global Program Manager R&D

Alfasigma is a privately held global healthcare company founded over 75 years ago in Italy, where it remains headquartered today in Bologna and Milan. The Group operates in over 100 markets spanning Europe, North and South America, Asia, and Africa.

Over three years ago, we embarked on a transformative journey to become a truly global innovative healthcare company with a leading focus on Gastrointestinal (GI) health. We have experienced remarkable growth, nearly doubled our revenues, expanding geographically, and integrating several key acquisitions. We have also evolved our portfolio, expanded into rare and specialty segments, and strengthened our pipeline and people's capabilities.

But our journey is far from complete! In fact, this is just the beginning of a bold new chapter in Alfasigma's history. We are committed to advancing innovation and leveraging our deep expertise to provide better health and a better quality of life for patients and consumers worldwide and expand our reach across diverse markets.

 

Scope of the Role

As a member of Alfasigma’s Global Program Management Office, the Program Manager contributes to the management of the company’s development programs and supports operational pipeline activities. This role ensures accurate project management information, monitors progress, identifies potential issues, and advises the Core Program Team on mitigative actions. The Program Manager collaborates closely with representatives from multiple departments—including Research, Non-clinical, CMC, Regulatory Affairs, and Clinical—placing them in a central position to manage cross-functional dependencies and report directly to the Program Director.


Your Role

  • Support the Program Director (PD) in leading the R&ED portfolio as a key liaison between functional sub-teams, program members, and other organizational units, including alliance partners when applicable.
  • Prepare and lead select Pre-clinical Global Program Team meetings, with PD support.
  • Develop high-level and detailed project schedules, support program budget development, set baselines for new projects and phases, and provide timely alerts and solutions to the PD regarding variances.
  • Monitor program sub-team deliverables to ensure execution aligns with strategy and functional plans; track milestones and deliverables.
  • Support program reporting, collecting and analyzing project performance data including timelines, budgets/resources, and other relevant metrics.
  • Lead the risk management process, including proactive risk identification, quantification, mitigation planning, and strategy definition.
  • Contribute to project strategy development, ensuring it is translated into robust and realistic project plans in collaboration with all relevant functions and the PD.
  • Assist in preparing presentations for senior management committees in partnership with the PD and other stakeholders.

Who You Are

  • Proficient in project management software (MS Project or equivalent).
  • Team player with excellent organizational, communication, and interpersonal skills across diverse functions.
  • Strong sense of urgency and patient centricity.
  • Able to work effectively under pressure, adaptable and flexible, maintaining a positive outlook.
  • Proactive and creative thinker, willing to challenge the status quo.
  • Fluent in English.

Education & Background:

  • Degree in a scientific discipline (BS, MS, Engineering, PhD, DVM).
  • Minimum 3 years’ experience in project management or planning, preferably in pharmaceutical or biotech industries.
  • Knowledge of all phases of drug development, from Discovery to Commercial.
  • Project management training or formal qualification is desirable; PMP certification is a plus.

Why Join Alfasigma:

At Alfasigma, we foster a culture where the courage to innovate is key to our success.
 We offer a competitive salary, comprehensive benefits, and extensive opportunities for professional growth and development.

Our commitment to people and patients is at the heart of everything we do. We value diversity and welcome individuals with unique perspectives and experiences. We believe that open-mindedness, collaboration, and a shared passion for innovation are essential to achieving meaningful progress.

Join Alfasigma and become part of a forward-thinking team dedicated to shaping the future of the pharmaceutical industry.